Manuscript: Mechanosensitive Ca2+ signaling and coordination is diminished in osteocytes of aged mice during ex vivo tibial loading

Prescient’s Andrea Campi’s doctoral research has yielded a published manuscript in Connective Tissue Research:

Mechanosensitive Ca²⁺ signaling and coordination is diminished in osteocytes of aged mice during ex vivo tibial loading

This work used a novel ex vivo model to demonstrate diminished mechanosensing and lack of signaling coordination in aged osteocyte networks in live bone, which may contribute to pathology of age-induced bone loss.